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Walter Rudolf Hess

The goal of physiological research is functional nature.

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For man also, in health and sickness, is not just the sum of his organs, but is indeed a human organism.

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At the beginning of all experimental work stands the choice of the appropriate technique of investigation.

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It must be born in mind that one does not see directly - as is the case in the exploration of the surface of the brain - where the electrodes are attacking.

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Exact information about the functional significance of the deep sections of the brain is only obtained by working through the brain histologically in serial section.

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In fact, quantitative findings of any material and energy changes preserve their full context only through their being seen and understood as parts of a natural order.

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This implies that the laws governing organic cohesion, the organization leading from the part to the whole, represent a biological uncertainty, indeed an uncertainty of the first order.

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The only positive finding which could be drawn from the first series, was the conclusion that the relationships obviously had a more complicated lay-out than had been thought, for the effects were so varied that no obedience to any law could be discovered.

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