Every chemical reaction has a transition state.

quote by Derek Harold Richard Barton
Added by Lucian Velea
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Many transition states have a well-defined preferred geometrical requirement.

quote by Derek Harold Richard Barton
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X-Ray crystallography is nowadays an accurate and rapid method of determining conformation in the crystal lattice, which conformation usually corresponds to the preferred conformation in solution.

quote by Derek Harold Richard Barton
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It does not seem, however, that organic chemists were much worried about barriers to rotation in organic molecules in general at that time because there was no technique available to demonstrate the phenomenon experimentally.

quote by Derek Harold Richard Barton
Added by Lucian Velea
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