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Arvid Carlsson

Well, in pharmacology, if the effect is local, it's of course absolutely awkward to use it in any other way than as a local treatment.

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In modern pharmacology it's so clear that even if you have a fixed dose of a drug, the individuals respond very differently to one and the same dose.

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Fluorine has a protecting action against caries, but this is a local effect. If you drink it, you are running the risk of all kinds of toxic actions.

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