Even if it had not been possible to reproduce the disease in animals and consequently to verify the hypothesis, this simple observation would have been sufficient to demonstrate the way in which the disease was propagated.

quote by Charles Jules Henry Nicole
Added by Lucian Velea
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I demonstrated the characteristics of experimental fever. It appears after an incubation period which is never less than five days. It follows the same pattern as natural fever in man, but is of shorter duration and less pronounced.

quote by Charles Jules Henry Nicole
Added by Lucian Velea
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Just as the only reservoir for the typhus virus in nature is provided by man, so the only vector of infection is the louse. The bite of the louse is not virulent immediately after the infecting meal. It becomes so only towards the 7th day following infection.

quote by Charles Jules Henry Nicole
Added by Lucian Velea
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